Genomeediting相关论文
In October 2020,Dr.Emmanuelle Charpentier and Dr.Jennifer Doudna won the Nobel Prize in Chemistry for their pioneering w......
A discussion on cotton transformation during the last decade (2010–2021); an update on present trend
The introduction of genetically modified (GM) cotton in 1996 in the US and its worldwide spread later rejuvenated cotton......
Genetic manipulation of mitochondrial DNA (mtDNA) could be harnessed for deciphering the gene function of mitochondria;i......
Genome-edited human induced pluripotent stem cells (iPSCs) hold great promise for therapeutic applications.However,low e......
Non-human Primate Models for Brain Disorders-Towards Genetic Manipulations via Innovative Technology
Modeling brain disorders has always been one of the key tasks in neurobiological studies.A wide range of organisms inclu......
Systematic Study of Impairing Effect on Terpenoid Biosynthesis in Escherichia coli Derived from Prom
In contrast to the classical notion that enzymes always carry out highly specific reaction towards particular substrate,......
Efficient Production of Fatty Alcohols by E.coli Modified with Tandem Repeats Assisted Genome Editin
Genome editing can introduce predetermined sequence changes to the target genome.In this work,a new genome editing metho......
The prokaryotic CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9, an RNA-guided endonuclease, is a......
Background: The CRISPR/Cas9 system is being used for genome editing purposes by many research groups in multiple plant s......
Ultra-rapid generation of genome-edited mice crucial for neurodevelopmental research via CRISPR/Cas9
Gene knockout mice and gene knockin mice are pivotal tools for studying higher-order life phenomenon in vivo,and also im......
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Genomic structure variation(GSV)is widely distributed in various organisms and is an important contributor to disease su......
In this article we summarize the development of vehicles for penetrating living cells, tissue and organisms with nucleic......
Improving the Efficiency of Precise Genome Editing with Site-Specific Cas9-Oligonucleotide Conjugate
Site-specific chemical conjugation of proteins can enhance their therapeutic and diagnostic utility but has seldom b......
Next-generation sequencers and genome editing technologies have played significant role in studying genomics in the ......
CRISPR/Cas9 system has recently been exploited for genome engineering.To reduce it down to practice particularly for......
The success in gene knockout by genome editing techniques is limited only in few model insects.Here, we reported a h......
Enhancing genetic gain becomes increasingly important in order to feed the world withincreasing population but decreasin......
The development of clustered regularly interspaced palindromic repeats (CRISPR)-associated protein (Cas) variants with a......
Genome editing by clustered regularly interspaced short palindromic sequences (CRISPR)/CRISPR-associated protein 9 (Cas9......
An enhanced CDA-like (eCDAL) was established from Japanese lamprey CDA1-like 4 to achieve a high editing frequency in a ......
Streptococcus canis Cas9 (ScCas9) is an RNA-guided endonuclease with NNG protospacer adjacent motif (PAM) specificity wh......
The clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated(Cas) protein 9 system(CRISPR/Cas......
The clustered regularly interspaced short palindromic repeats(CRISPR)-associated endonuclease 9(CRISPR/Cas9) system has ......
Many genome editing tools have been developed and new ones are anticipated; some have been extensively applied in plant ......
Genome editing in Drosophila melanogaster： from basic genome engineering to the multipurpose CRISPR-
Nowadays, genome editing tools are indispensable for studying gene function in order to increase our knowledge of bioche......
The clustered regularly interspaced short palindromic repeats(CRISPR)-associated protein 9(CRISPR-Cas9) system provides ......
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9(CRISPR/Cas9) genome editi......
Flowering time is an important agronomic trait for soybean yield and adaptation. However, the genetic basis of soybean a......
Gene editing technology provides important technical basics for the research in plant functional genes and crop genetic ......
The clustered regularly interspaced short palindromic repeats(CRISPR)-associated nuclease 9(Cas9)-based genome editing t......
Since genetic engineering of pigs can benefit both biomedicine and agriculture,selecting a suitable gene promoter is cri......
The rabbit has been recognized as a valuable model in various biomedical and biological research fields because of its i......
